2016 head-to-head · Midsize Car

2016 Lexus GS vs Mercedes-Benz E-Class

MPG, range and what each one really costs you to fuel, from official EPA ratings and recalculated with your own gas and electricity prices.

Swap sides
✓ Cheaper to run
$2,279/ year to fuel
26 MPG
✓ Cheaper to run
$2,576/ year to fuel
23 MPG

The 2016 Lexus GS is the cheaper one to run. Driving 15,000 miles a year with $3.95/gal premium gas, it costs about $2,279 a year to fuel (26 MPG), versus $2,576 for the 2016 Mercedes-Benz E-Class (23 MPG). That's roughly $297 a year, or about $1,486 over five years.

Your numbers

Change these to match your driving and local prices. Every figure and chart on this page updates.

Fuel cost over 10 years

  • Lexus GS
  • Mercedes-Benz E-Class

Side by side

Lexus GSMercedes-Benz E-Class
$2,279 Your annual fuel cost $2,576
26 MPG Combined efficiency 23 MPG
22 MPG City 20 MPG
32 MPG Highway 29 MPG
99 cu ft Passenger volume 81 cu ft
14 cu ft Cargo volume 11 cu ft
345 g/mi Tailpipe CO₂ (g/mi) 377 g/mi
6/10 EPA fuel economy score 5/10
6/10 EPA greenhouse gas score 5/10
Gas Powertrain Gas
Premium gasoline Fuel Premium gasoline
2.0L 4-cyl turbo Engine / motor 3.0L 6-cyl turbo
8-speed automatic Transmission 7-speed automatic
RWD Drivetrain RWD

✓ marks the better value. EPA scores run 1–10 (10 is best). Volumes come from the EPA interior volume index and aren't published for every body style.

Lexus GS vs Mercedes-Benz E-Class across model years

  • Lexus GS
  • Mercedes-Benz E-Class

Annual fuel cost of the most efficient configuration of each model year, at your prices. Click a point to open that year.

How they differ

Per EPA interior volume figures, the Lexus GS has more passenger space (99 vs. 81 cu ft); the Lexus GS has more cargo space (14 vs. 11 cu ft).

Among 67 2016 midsize cars, the Lexus GS ranks 49th and the Mercedes-Benz E-Class 53rd for lowest fuel cost.

Frequently asked questions

Which is more fuel-efficient, the 2016 Lexus GS or the 2016 Mercedes-Benz E-Class?

Measured by cost to drive, the Lexus GS. The Lexus GS is rated 26 MPG combined and the Mercedes-Benz E-Class 23 MPG (EPA, most efficient configuration of each).

How much does it cost to fuel the 2016 Lexus GS vs. the Mercedes-Benz E-Class per year?

At 15,000 miles a year with $3.95/gal premium gas, about $2,279 for the Lexus GS and $2,576 for the Mercedes-Benz E-Class.

Which has more cargo space?

The Lexus GS, with 14 cu ft of luggage volume versus 11 cu ft (EPA interior volume index).

Lexus GS vs Mercedes-Benz E-Class in other years

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