2020 head-to-head · Midsize Car

2020 Lexus LS vs Mercedes-Benz E-Class

MPG, range and what each one really costs you to fuel, from official EPA ratings and recalculated with your own gas and electricity prices.

Swap sides
✓ Cheaper to run
$2,576/ year to fuel
23 MPG
✓ Cheaper to run
$2,279/ year to fuel
26 MPG

The 2020 Mercedes-Benz E-Class is the cheaper one to run. Driving 15,000 miles a year with $3.95/gal premium gas, it costs about $2,279 a year to fuel (26 MPG), versus $2,576 for the 2020 Lexus LS (23 MPG). That's roughly $297 a year, or about $1,486 over five years.

Your numbers

Change these to match your driving and local prices. Every figure and chart on this page updates.

Fuel cost over 10 years

  • Lexus LS
  • Mercedes-Benz E-Class

Side by side

Lexus LSMercedes-Benz E-Class
$2,576 Your annual fuel cost $2,279
23 MPG Combined efficiency 26 MPG
19 MPG City 23 MPG
30 MPG Highway 32 MPG
99 cu ft Passenger volume 98 cu ft
13 cu ft Cargo volume 13 cu ft
389 g/mi Tailpipe CO₂ (g/mi) 336 g/mi
5/10 EPA fuel economy score 5/10
5/10 EPA greenhouse gas score 5/10
Gas Powertrain Gas
Premium gasoline Fuel Premium gasoline
3.4L 6-cyl turbo Engine / motor 2.0L 4-cyl turbo
10-speed automatic Transmission 9-speed automatic
RWD Drivetrain RWD

✓ marks the better value. EPA scores run 1–10 (10 is best). Volumes come from the EPA interior volume index and aren't published for every body style.

Lexus LS vs Mercedes-Benz E-Class across model years

  • Lexus LS
  • Mercedes-Benz E-Class

Annual fuel cost of the most efficient configuration of each model year, at your prices. Click a point to open that year.

How they differ

Among 64 2020 midsize cars, the Lexus LS ranks 54th and the Mercedes-Benz E-Class 48th for lowest fuel cost.

Frequently asked questions

Which is more fuel-efficient, the 2020 Lexus LS or the 2020 Mercedes-Benz E-Class?

Measured by cost to drive, the Mercedes-Benz E-Class. The Lexus LS is rated 23 MPG combined and the Mercedes-Benz E-Class 26 MPG (EPA, most efficient configuration of each).

How much does it cost to fuel the 2020 Lexus LS vs. the Mercedes-Benz E-Class per year?

At 15,000 miles a year with $3.95/gal premium gas, about $2,576 for the Lexus LS and $2,279 for the Mercedes-Benz E-Class.

Lexus LS vs Mercedes-Benz E-Class in other years

More 2020 comparisons

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