2021 head-to-head · Large Car

2021 Audi A8 Hybrid vs Mercedes-Benz S-Class Hybrid

MPG, range and what each one really costs you to fuel, from official EPA ratings and recalculated with your own gas and electricity prices.

Swap sides
✓ Cheaper to run
$2,821/ year to fuel
21 MPG
✓ Cheaper to run
$2,469/ year to fuel
24 MPG

The 2021 Mercedes-Benz S-Class Hybrid is the cheaper one to run. Driving 15,000 miles a year with $3.95/gal premium gas, it costs about $2,469 a year to fuel (24 MPG), versus $2,821 for the 2021 Audi A8 Hybrid (21 MPG). That's roughly $353 a year, or about $1,763 over five years.

Your numbers

Change these to match your driving and local prices. Every figure and chart on this page updates.

Fuel cost over 10 years

  • Audi A8 Hybrid
  • Mercedes-Benz S-Class Hybrid

Side by side

Audi A8 HybridMercedes-Benz S-Class Hybrid
$2,821 Your annual fuel cost $2,469
21 MPG Combined efficiency 24 MPG
17 MPG City 20 MPG
26 MPG Highway 29 MPG
111 cu ft Passenger volume 112 cu ft
13 cu ft Cargo volume 13 cu ft
430 g/mi Tailpipe CO₂ (g/mi) 372 g/mi
4/10 EPA fuel economy score 5/10
4/10 EPA greenhouse gas score 5/10
Hybrid Powertrain Hybrid
Premium gasoline Fuel Premium gasoline
3.0L 6-cyl turbo Engine / motor 3.0L 6-cyl
8-speed automatic Transmission 9-speed automatic
AWD Drivetrain 4WD

✓ marks the better value. EPA scores run 1–10 (10 is best). Volumes come from the EPA interior volume index and aren't published for every body style.

Audi A8 Hybrid vs Mercedes-Benz S-Class Hybrid across model years

  • Audi A8 Hybrid
  • Mercedes-Benz S-Class Hybrid

Annual fuel cost of the most efficient configuration of each model year, at your prices. Click a point to open that year.

How they differ

Among 27 2021 large cars, the Audi A8 Hybrid ranks 21st and the Mercedes-Benz S-Class Hybrid 20th for lowest fuel cost.

Frequently asked questions

Which is more fuel-efficient, the 2021 Audi A8 Hybrid or the 2021 Mercedes-Benz S-Class Hybrid?

Measured by cost to drive, the Mercedes-Benz S-Class Hybrid. The Audi A8 Hybrid is rated 21 MPG combined and the Mercedes-Benz S-Class Hybrid 24 MPG (EPA, most efficient configuration of each).

How much does it cost to fuel the 2021 Audi A8 Hybrid vs. the Mercedes-Benz S-Class Hybrid per year?

At 15,000 miles a year with $3.95/gal premium gas, about $2,821 for the Audi A8 Hybrid and $2,469 for the Mercedes-Benz S-Class Hybrid.

Audi A8 Hybrid vs Mercedes-Benz S-Class Hybrid in other years

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