2021 head-to-head · Compact Car
2021 Cadillac CT4 vs Mercedes-Benz S-Class
MPG, range and what each one really costs you to fuel, from official EPA ratings and recalculated with your own gas and electricity prices.
The 2021 Cadillac CT4 is the cheaper one to run. Driving 15,000 miles a year with $3.95/gal premium gas, it costs about $2,194 a year to fuel (27 MPG), versus $2,962 for the 2021 Mercedes-Benz S-Class (20 MPG). That's roughly $768 a year, or about $3,840 over five years.
Your numbers
Change these to match your driving and local prices. Every figure and chart on this page updates.
Fuel cost over 10 years
- Cadillac CT4
- Mercedes-Benz S-Class
Side by side
| Cadillac CT4 | Mercedes-Benz S-Class | |
|---|---|---|
| $2,194 | Your annual fuel cost | $2,962 |
| 27 MPG | Combined efficiency | 20 MPG |
| 23 MPG | City | 16 MPG |
| 34 MPG | Highway | 26 MPG |
| 90 cu ft | Passenger volume | 88 cu ft |
| 13 cu ft | Cargo volume | 7 cu ft |
| 327 g/mi | Tailpipe CO₂ (g/mi) | 454 g/mi |
| 6/10 | EPA fuel economy score | 4/10 |
| 6/10 | EPA greenhouse gas score | 4/10 |
| Gas | Powertrain | Gas |
| Premium gasoline | Fuel | Premium gasoline |
| 2.0L 4-cyl turbo | Engine / motor | 4.0L 8-cyl turbo |
| 8-speed automatic | Transmission | 9-speed automatic |
| RWD | Drivetrain | RWD |
✓ marks the better value. EPA scores run 1–10 (10 is best). Volumes come from the EPA interior volume index and aren't published for every body style.
Cadillac CT4 vs Mercedes-Benz S-Class across model years
- Cadillac CT4
- Mercedes-Benz S-Class
Annual fuel cost of the most efficient configuration of each model year, at your prices. Click a point to open that year.
How they differ
Per EPA interior volume figures, the Cadillac CT4 has more cargo space (13 vs. 7 cu ft).
Among 37 2021 compact cars, the Cadillac CT4 ranks 26th and the Mercedes-Benz S-Class 35th for lowest fuel cost.
Frequently asked questions
Which is more fuel-efficient, the 2021 Cadillac CT4 or the 2021 Mercedes-Benz S-Class?
Measured by cost to drive, the Cadillac CT4. The Cadillac CT4 is rated 27 MPG combined and the Mercedes-Benz S-Class 20 MPG (EPA, most efficient configuration of each).
How much does it cost to fuel the 2021 Cadillac CT4 vs. the Mercedes-Benz S-Class per year?
At 15,000 miles a year with $3.95/gal premium gas, about $2,194 for the Cadillac CT4 and $2,962 for the Mercedes-Benz S-Class.
Which has more cargo space?
The Cadillac CT4, with 13 cu ft of luggage volume versus 7 cu ft (EPA interior volume index).
More 2021 comparisons
Cadillac CT4 vs…
Or compare the 2021 Cadillac CT4 with anything else: