2022 head-to-head · Compact Car

2022 Acura TLX vs Mercedes-Benz CLS-Class Hybrid

MPG, range and what each one really costs you to fuel, from official EPA ratings and recalculated with your own gas and electricity prices.

Swap sides
✓ Cheaper to run
$2,370/ year to fuel
25 MPG
✓ Cheaper to run
$2,370/ year to fuel
25 MPG

4WD · 3.0L 6-cyl turbo · 9-speed automatic · 25 MPG

On fuel costs these two are nearly tied. Driving 15,000 miles a year with $3.95/gal premium gas, the most efficient 2022 Acura TLX (25 MPG) costs about $2,370 a year to fuel and the 2022 Mercedes-Benz CLS-Class Hybrid (25 MPG) about $2,370.

Your numbers

Change these to match your driving and local prices. Every figure and chart on this page updates.

Fuel cost over 10 years

  • Acura TLX
  • Mercedes-Benz CLS-Class Hybrid

Side by side

Acura TLXMercedes-Benz CLS-Class Hybrid
$2,370 Your annual fuel cost $2,370
25 MPG Combined efficiency 25 MPG
22 MPG City 22 MPG
31 MPG Highway 30 MPG
93 cu ft Passenger volume 93 cu ft
14 cu ft Cargo volume 12 cu ft
352 g/mi Tailpipe CO₂ (g/mi) 357 g/mi
5/10 EPA fuel economy score 5/10
5/10 EPA greenhouse gas score 5/10
Gas Powertrain Hybrid
Premium gasoline Fuel Premium gasoline
2.0L 4-cyl turbo Engine / motor 3.0L 6-cyl turbo
10-speed automatic Transmission 9-speed automatic
FWD Drivetrain 4WD

✓ marks the better value. EPA scores run 1–10 (10 is best). Volumes come from the EPA interior volume index and aren't published for every body style.

Acura TLX vs Mercedes-Benz CLS-Class Hybrid across model years

  • Acura TLX
  • Mercedes-Benz CLS-Class Hybrid

Annual fuel cost of the most efficient configuration of each model year, at your prices. Click a point to open that year.

How they differ

Per EPA interior volume figures, the Acura TLX has more cargo space (14 vs. 12 cu ft).

Among 33 2022 compact cars, the Acura TLX ranks 29th and the Mercedes-Benz CLS-Class Hybrid 27th for lowest fuel cost.

The powertrains differ: the Acura TLX is a conventional gas model, while the Mercedes-Benz CLS-Class Hybrid is a full hybrid.

Frequently asked questions

How much does it cost to fuel the 2022 Acura TLX vs. the Mercedes-Benz CLS-Class Hybrid per year?

At 15,000 miles a year with $3.95/gal premium gas, about $2,370 for the Acura TLX and $2,370 for the Mercedes-Benz CLS-Class Hybrid.

Which has more cargo space?

The Acura TLX, with 14 cu ft of luggage volume versus 12 cu ft (EPA interior volume index).

Acura TLX vs Mercedes-Benz CLS-Class Hybrid in other years

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