2022 head-to-head · Subcompact Car
2022 Audi S5 vs Mercedes-Benz C-Class
MPG, range and what each one really costs you to fuel, from official EPA ratings and recalculated with your own gas and electricity prices.
The 2022 Mercedes-Benz C-Class is the cheaper one to run. Driving 15,000 miles a year with $3.95/gal premium gas, it costs about $2,370 a year to fuel (25 MPG), versus $2,469 for the 2022 Audi S5 (24 MPG). That's roughly $99 a year, or about $494 over five years.
Your numbers
Change these to match your driving and local prices. Every figure and chart on this page updates.
Fuel cost over 10 years
- Audi S5
- Mercedes-Benz C-Class
Side by side
| Audi S5 | Mercedes-Benz C-Class | |
|---|---|---|
| $2,469 | Your annual fuel cost | $2,370 |
| 24 MPG | Combined efficiency | 25 MPG |
| 21 MPG | City | 22 MPG |
| 30 MPG | Highway | 31 MPG |
| 84 cu ft | Passenger volume | 79 cu ft |
| 11 cu ft | Cargo volume | 10 cu ft |
| 363 g/mi | Tailpipe CO₂ (g/mi) | 350 g/mi |
| 5/10 | EPA fuel economy score | 5/10 |
| 5/10 | EPA greenhouse gas score | 5/10 |
| Gas | Powertrain | Gas |
| Premium gasoline | Fuel | Premium gasoline |
| 3.0L 6-cyl turbo | Engine / motor | 2.0L 4-cyl turbo |
| 8-speed automatic | Transmission | 9-speed automatic |
| 4WD | Drivetrain | AWD |
✓ marks the better value. EPA scores run 1–10 (10 is best). Volumes come from the EPA interior volume index and aren't published for every body style.
Audi S5 vs Mercedes-Benz C-Class across model years
- Audi S5
- Mercedes-Benz C-Class
Annual fuel cost of the most efficient configuration of each model year, at your prices. Click a point to open that year.
How they differ
Per EPA interior volume figures, the Audi S5 has more passenger space (84 vs. 79 cu ft); the Audi S5 has more cargo space (11 vs. 10 cu ft).
Among 34 2022 subcompact cars, the Audi S5 ranks 22nd and the Mercedes-Benz C-Class 18th for lowest fuel cost.
Frequently asked questions
Which is more fuel-efficient, the 2022 Audi S5 or the 2022 Mercedes-Benz C-Class?
Measured by cost to drive, the Mercedes-Benz C-Class. The Audi S5 is rated 24 MPG combined and the Mercedes-Benz C-Class 25 MPG (EPA, most efficient configuration of each).
How much does it cost to fuel the 2022 Audi S5 vs. the Mercedes-Benz C-Class per year?
At 15,000 miles a year with $3.95/gal premium gas, about $2,469 for the Audi S5 and $2,370 for the Mercedes-Benz C-Class.
Which has more cargo space?
The Audi S5, with 11 cu ft of luggage volume versus 10 cu ft (EPA interior volume index).
Audi S5 vs Mercedes-Benz C-Class in other years
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