2024 head-to-head · Midsize Car

2024 Lexus LS Hybrid vs Mercedes-Benz E-Class Hybrid

MPG, range and what each one really costs you to fuel, from official EPA ratings and recalculated with your own gas and electricity prices.

Swap sides
✓ Cheaper to run
$2,370/ year to fuel
25 MPG

AWD · 3.5L 6-cyl · CVT · 25 MPG

✓ Cheaper to run
$2,194/ year to fuel
27 MPG

The 2024 Mercedes-Benz E-Class Hybrid is the cheaper one to run. Driving 15,000 miles a year with $3.95/gal premium gas, it costs about $2,194 a year to fuel (27 MPG), versus $2,370 for the 2024 Lexus LS Hybrid (25 MPG). That's roughly $176 a year, or about $878 over five years.

Your numbers

Change these to match your driving and local prices. Every figure and chart on this page updates.

Fuel cost over 10 years

  • Lexus LS Hybrid
  • Mercedes-Benz E-Class Hybrid

Side by side

Lexus LS HybridMercedes-Benz E-Class Hybrid
$2,370 Your annual fuel cost $2,194
25 MPG Combined efficiency 27 MPG
22 MPG City 24 MPG
29 MPG Highway 33 MPG
99 cu ft Passenger volume 100 cu ft
12 cu ft Cargo volume 13 cu ft
358 g/mi Tailpipe CO₂ (g/mi) 327 g/mi
5/10 EPA fuel economy score 5/10
5/10 EPA greenhouse gas score 5/10
Hybrid Powertrain Hybrid
Premium gasoline Fuel Premium gasoline
3.5L 6-cyl Engine / motor 2.0L 4-cyl turbo
CVT Transmission 9-speed automatic
AWD Drivetrain AWD

✓ marks the better value. EPA scores run 1–10 (10 is best). Volumes come from the EPA interior volume index and aren't published for every body style.

Lexus LS Hybrid vs Mercedes-Benz E-Class Hybrid across model years

  • Lexus LS Hybrid
  • Mercedes-Benz E-Class Hybrid

Annual fuel cost of the most efficient configuration of each model year, at your prices. Click a point to open that year.

How they differ

Per EPA interior volume figures, the Mercedes-Benz E-Class Hybrid has more cargo space (13 vs. 12 cu ft).

Among 43 2024 midsize cars, the Lexus LS Hybrid ranks 32nd and the Mercedes-Benz E-Class Hybrid 27th for lowest fuel cost.

Frequently asked questions

Which is more fuel-efficient, the 2024 Lexus LS Hybrid or the 2024 Mercedes-Benz E-Class Hybrid?

Measured by cost to drive, the Mercedes-Benz E-Class Hybrid. The Lexus LS Hybrid is rated 25 MPG combined and the Mercedes-Benz E-Class Hybrid 27 MPG (EPA, most efficient configuration of each).

How much does it cost to fuel the 2024 Lexus LS Hybrid vs. the Mercedes-Benz E-Class Hybrid per year?

At 15,000 miles a year with $3.95/gal premium gas, about $2,370 for the Lexus LS Hybrid and $2,194 for the Mercedes-Benz E-Class Hybrid.

Which has more cargo space?

The Mercedes-Benz E-Class Hybrid, with 13 cu ft of luggage volume versus 12 cu ft (EPA interior volume index).

Lexus LS Hybrid vs Mercedes-Benz E-Class Hybrid in other years

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