2025 head-to-head · Large Car
2025 Mercedes-Benz S-Class Hybrid vs Porsche Panamera
MPG, range and what each one really costs you to fuel, from official EPA ratings and recalculated with your own gas and electricity prices.
The 2025 Mercedes-Benz S-Class Hybrid is the cheaper one to run. Driving 15,000 miles a year with $3.95/gal premium gas, it costs about $2,469 a year to fuel (24 MPG), versus $2,821 for the 2025 Porsche Panamera (21 MPG). That's roughly $353 a year, or about $1,763 over five years.
Your numbers
Change these to match your driving and local prices. Every figure and chart on this page updates.
Fuel cost over 10 years
- Mercedes-Benz S-Class Hybrid
- Porsche Panamera
Side by side
| Mercedes-Benz S-Class Hybrid | Porsche Panamera | |
|---|---|---|
| $2,469 | Your annual fuel cost | $2,821 |
| 24 MPG | Combined efficiency | 21 MPG |
| 21 MPG | City | 18 MPG |
| 31 MPG | Highway | 25 MPG |
| 112 cu ft | Passenger volume | 98 cu ft |
| 13 cu ft | Cargo volume | 27 cu ft |
| 364 g/mi | Tailpipe CO₂ (g/mi) | 431 g/mi |
| 5/10 | EPA fuel economy score | 4/10 |
| 5/10 | EPA greenhouse gas score | 4/10 |
| Hybrid | Powertrain | Gas |
| Premium gasoline | Fuel | Premium gasoline |
| 3.0L 6-cyl turbo | Engine / motor | 2.9L 6-cyl turbo |
| 9-speed automatic | Transmission | 8-speed dual-clutch |
| AWD | Drivetrain | RWD |
✓ marks the better value. EPA scores run 1–10 (10 is best). Volumes come from the EPA interior volume index and aren't published for every body style.
Mercedes-Benz S-Class Hybrid vs Porsche Panamera across model years
- Mercedes-Benz S-Class Hybrid
- Porsche Panamera
Annual fuel cost of the most efficient configuration of each model year, at your prices. Click a point to open that year.
How they differ
Per EPA interior volume figures, the Mercedes-Benz S-Class Hybrid has more passenger space (112 vs. 98 cu ft); the Porsche Panamera has more cargo space (27 vs. 13 cu ft).
Among 25 2025 large cars, the Mercedes-Benz S-Class Hybrid ranks 16th and the Porsche Panamera 19th for lowest fuel cost.
The powertrains differ: the Mercedes-Benz S-Class Hybrid is a full hybrid, while the Porsche Panamera is a conventional gas model.
Frequently asked questions
Which is more fuel-efficient, the 2025 Mercedes-Benz S-Class Hybrid or the 2025 Porsche Panamera?
Measured by cost to drive, the Mercedes-Benz S-Class Hybrid. The Mercedes-Benz S-Class Hybrid is rated 24 MPG combined and the Porsche Panamera 21 MPG (EPA, most efficient configuration of each).
How much does it cost to fuel the 2025 Mercedes-Benz S-Class Hybrid vs. the Porsche Panamera per year?
At 15,000 miles a year with $3.95/gal premium gas, about $2,469 for the Mercedes-Benz S-Class Hybrid and $2,821 for the Porsche Panamera.
Which has more cargo space?
The Porsche Panamera, with 27 cu ft of luggage volume versus 13 cu ft (EPA interior volume index).
Mercedes-Benz S-Class Hybrid vs Porsche Panamera in other years
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