2022 head-to-head · Midsize Car
2022 Audi A6 Hybrid vs Mercedes-Benz E-Class
MPG, range and what each one really costs you to fuel, from official EPA ratings and recalculated with your own gas and electricity prices.
On fuel costs these two are nearly tied. Driving 15,000 miles a year with $3.95/gal premium gas, the most efficient 2022 Audi A6 Hybrid (26 MPG) costs about $2,279 a year to fuel and the 2022 Mercedes-Benz E-Class (26 MPG) about $2,279.
Your numbers
Change these to match your driving and local prices. Every figure and chart on this page updates.
Fuel cost over 10 years
- Audi A6 Hybrid
- Mercedes-Benz E-Class
Side by side
| Audi A6 Hybrid | Mercedes-Benz E-Class | |
|---|---|---|
| $2,279 | Your annual fuel cost | $2,279 |
| 26 MPG | Combined efficiency | 26 MPG |
| 23 MPG | City | 23 MPG |
| 32 MPG | Highway | 31 MPG |
| 99 cu ft | Passenger volume | 98 cu ft |
| 14 cu ft | Cargo volume | 13 cu ft |
| 335 g/mi | Tailpipe CO₂ (g/mi) | 342 g/mi |
| 5/10 | EPA fuel economy score | 5/10 |
| 5/10 | EPA greenhouse gas score | 5/10 |
| Hybrid | Powertrain | Gas |
| Premium gasoline | Fuel | Premium gasoline |
| 2.0L 4-cyl turbo | Engine / motor | 2.0L 4-cyl turbo |
| 7-speed dual-clutch | Transmission | 9-speed automatic |
| AWD | Drivetrain | RWD |
✓ marks the better value. EPA scores run 1–10 (10 is best). Volumes come from the EPA interior volume index and aren't published for every body style.
Audi A6 Hybrid vs Mercedes-Benz E-Class across model years
- Audi A6 Hybrid
- Mercedes-Benz E-Class
Annual fuel cost of the most efficient configuration of each model year, at your prices. Click a point to open that year.
How they differ
Per EPA interior volume figures, the Audi A6 Hybrid has more cargo space (14 vs. 13 cu ft).
Among 54 2022 midsize cars, the Audi A6 Hybrid ranks 40th and the Mercedes-Benz E-Class 39th for lowest fuel cost.
The powertrains differ: the Audi A6 Hybrid is a full hybrid, while the Mercedes-Benz E-Class is a conventional gas model.
Frequently asked questions
How much does it cost to fuel the 2022 Audi A6 Hybrid vs. the Mercedes-Benz E-Class per year?
At 15,000 miles a year with $3.95/gal premium gas, about $2,279 for the Audi A6 Hybrid and $2,279 for the Mercedes-Benz E-Class.
Which has more cargo space?
The Audi A6 Hybrid, with 14 cu ft of luggage volume versus 13 cu ft (EPA interior volume index).
Audi A6 Hybrid vs Mercedes-Benz E-Class in other years
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