2022 head-to-head · Midsize Car

2022 Cadillac CT5 vs Lexus ES

MPG, range and what each one really costs you to fuel, from official EPA ratings and recalculated with your own gas and electricity prices.

Swap sides
✓ Cheaper to run
$2,194/ year to fuel
27 MPG
✓ Cheaper to run
$1,661/ year to fuel
28 MPG

The 2022 Lexus ES is the cheaper one to run. Driving 15,000 miles a year with $3.95/gal premium gas and $3.10/gal regular gas, it costs about $1,661 a year to fuel (28 MPG), versus $2,194 for the 2022 Cadillac CT5 (27 MPG). That's roughly $534 a year, or about $2,669 over five years.

Your numbers

Change these to match your driving and local prices. Every figure and chart on this page updates.

Fuel cost over 10 years

  • Cadillac CT5
  • Lexus ES

Side by side

Cadillac CT5Lexus ES
$2,194 Your annual fuel cost $1,661
27 MPG Combined efficiency 28 MPG
23 MPG City 25 MPG
33 MPG Highway 34 MPG
99 cu ft Passenger volume 97 cu ft
11 cu ft Cargo volume 14 cu ft
333 g/mi Tailpipe CO₂ (g/mi) 315 g/mi
6/10 EPA fuel economy score 6/10
6/10 EPA greenhouse gas score 6/10
Gas Powertrain Gas
Premium gasoline Fuel Regular gasoline
2.0L 4-cyl turbo Engine / motor 2.5L 4-cyl
10-speed automatic Transmission 8-speed automatic
RWD Drivetrain AWD

✓ marks the better value. EPA scores run 1–10 (10 is best). Volumes come from the EPA interior volume index and aren't published for every body style.

Cadillac CT5 vs Lexus ES across model years

  • Cadillac CT5
  • Lexus ES

Annual fuel cost of the most efficient configuration of each model year, at your prices. Click a point to open that year.

How they differ

Per EPA interior volume figures, the Lexus ES has more cargo space (14 vs. 11 cu ft).

Among 54 2022 midsize cars, the Cadillac CT5 ranks 38th and the Lexus ES 27th for lowest fuel cost.

Frequently asked questions

Which is more fuel-efficient, the 2022 Cadillac CT5 or the 2022 Lexus ES?

Measured by cost to drive, the Lexus ES. The Cadillac CT5 is rated 27 MPG combined and the Lexus ES 28 MPG (EPA, most efficient configuration of each).

How much does it cost to fuel the 2022 Cadillac CT5 vs. the Lexus ES per year?

At 15,000 miles a year with $3.95/gal premium gas and $3.10/gal regular gas, about $2,194 for the Cadillac CT5 and $1,661 for the Lexus ES.

Which has more cargo space?

The Lexus ES, with 14 cu ft of luggage volume versus 11 cu ft (EPA interior volume index).

Cadillac CT5 vs Lexus ES in other years

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