2024 head-to-head · Midsize Car

2024 Infiniti Q50 vs Mercedes-Benz E-Class Hybrid

MPG, range and what each one really costs you to fuel, from official EPA ratings and recalculated with your own gas and electricity prices.

Swap sides
✓ Cheaper to run
$2,576/ year to fuel
23 MPG
✓ Cheaper to run
$2,194/ year to fuel
27 MPG

The 2024 Mercedes-Benz E-Class Hybrid is the cheaper one to run. Driving 15,000 miles a year with $3.95/gal premium gas, it costs about $2,194 a year to fuel (27 MPG), versus $2,576 for the 2024 Infiniti Q50 (23 MPG). That's roughly $382 a year, or about $1,908 over five years.

Your numbers

Change these to match your driving and local prices. Every figure and chart on this page updates.

Fuel cost over 10 years

  • Infiniti Q50
  • Mercedes-Benz E-Class Hybrid

Side by side

Infiniti Q50Mercedes-Benz E-Class Hybrid
$2,576 Your annual fuel cost $2,194
23 MPG Combined efficiency 27 MPG
20 MPG City 24 MPG
29 MPG Highway 33 MPG
100 cu ft Passenger volume 100 cu ft
14 cu ft Cargo volume 13 cu ft
388 g/mi Tailpipe CO₂ (g/mi) 327 g/mi
5/10 EPA fuel economy score 5/10
5/10 EPA greenhouse gas score 5/10
Gas Powertrain Hybrid
Premium gasoline Fuel Premium gasoline
3.0L 6-cyl turbo Engine / motor 2.0L 4-cyl turbo
7-speed automatic Transmission 9-speed automatic
RWD Drivetrain AWD

✓ marks the better value. EPA scores run 1–10 (10 is best). Volumes come from the EPA interior volume index and aren't published for every body style.

Infiniti Q50 vs Mercedes-Benz E-Class Hybrid across model years

  • Infiniti Q50
  • Mercedes-Benz E-Class Hybrid

Annual fuel cost of the most efficient configuration of each model year, at your prices. Click a point to open that year.

How they differ

Per EPA interior volume figures, the Infiniti Q50 has more cargo space (14 vs. 13 cu ft).

Among 43 2024 midsize cars, the Infiniti Q50 ranks 35th and the Mercedes-Benz E-Class Hybrid 27th for lowest fuel cost.

The powertrains differ: the Infiniti Q50 is a conventional gas model, while the Mercedes-Benz E-Class Hybrid is a full hybrid.

Frequently asked questions

Which is more fuel-efficient, the 2024 Infiniti Q50 or the 2024 Mercedes-Benz E-Class Hybrid?

Measured by cost to drive, the Mercedes-Benz E-Class Hybrid. The Infiniti Q50 is rated 23 MPG combined and the Mercedes-Benz E-Class Hybrid 27 MPG (EPA, most efficient configuration of each).

How much does it cost to fuel the 2024 Infiniti Q50 vs. the Mercedes-Benz E-Class Hybrid per year?

At 15,000 miles a year with $3.95/gal premium gas, about $2,576 for the Infiniti Q50 and $2,194 for the Mercedes-Benz E-Class Hybrid.

Which has more cargo space?

The Infiniti Q50, with 14 cu ft of luggage volume versus 13 cu ft (EPA interior volume index).

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