2025 head-to-head · Midsize Car

2025 Alfa Romeo Giulia vs Mercedes-Benz E-Class Plug-in Hybrid

MPG, range and what each one really costs you to fuel, from official EPA ratings and recalculated with your own gas and electricity prices.

Swap sides
✓ Cheaper to run
$2,194/ year to fuel
27 MPG
✓ Cheaper to run
$1,847/ year to fuel
59 MPGe + 23 MPG

AWD · 3.0L 6-cyl turbo · 9-speed automatic · 59 MPGe + 23 MPG

The 2025 Mercedes-Benz E-Class Plug-in Hybrid is the cheaper one to run. Driving 15,000 miles a year with $3.95/gal premium gas and 18¢/kWh electricity, it costs about $1,847 a year to fuel (59 MPGe + 23 MPG), versus $2,194 for the 2025 Alfa Romeo Giulia (27 MPG). That's roughly $347 a year, or about $1,737 over five years.

Your numbers

Change these to match your driving and local prices. Every figure and chart on this page updates.

Fuel cost over 10 years

  • Alfa Romeo Giulia
  • Mercedes-Benz E-Class Plug-in Hybrid

Side by side

Alfa Romeo GiuliaMercedes-Benz E-Class Plug-in Hybrid
$2,194 Your annual fuel cost $1,847
27 MPG Combined efficiency 59 MPGe + 23 MPG
24 MPG City 54 MPGe / 21 MPG
33 MPG Highway 65 MPGe / 26 MPG
— Electricity use (kWh/100 mi) 57 kWh
— Driving range 410 mi
— All-electric range 43 mi
100 cu ft Passenger volume 100 cu ft
12 cu ft Cargo volume 13 cu ft
330 g/mi Tailpipe CO₂ (g/mi) 117 g/mi
5/10 EPA fuel economy score 7/10
5/10 EPA greenhouse gas score 9/10
— Charge time at 240V 2.8 hrs
Gas Powertrain Plug-in hybrid
Premium gasoline Fuel Premium gas + electricity
2.0L 4-cyl turbo Engine / motor 3.0L 6-cyl turbo
8-speed automatic Transmission 9-speed automatic
RWD Drivetrain AWD

✓ marks the better value. EPA scores run 1–10 (10 is best). Volumes come from the EPA interior volume index and aren't published for every body style.

Alfa Romeo Giulia vs Mercedes-Benz E-Class Plug-in Hybrid across model years

  • Alfa Romeo Giulia
  • Mercedes-Benz E-Class Plug-in Hybrid

Annual fuel cost of the most efficient configuration of each model year, at your prices. Click a point to open that year.

How they differ

Per EPA interior volume figures, the Mercedes-Benz E-Class Plug-in Hybrid has more cargo space (13 vs. 12 cu ft).

Among 42 2025 midsize cars, the Alfa Romeo Giulia ranks 28th and the Mercedes-Benz E-Class Plug-in Hybrid 23rd for lowest fuel cost.

The powertrains differ: the Alfa Romeo Giulia is a conventional gas model, while the Mercedes-Benz E-Class Plug-in Hybrid is a plug-in hybrid.

Frequently asked questions

Which is more fuel-efficient, the 2025 Alfa Romeo Giulia or the 2025 Mercedes-Benz E-Class Plug-in Hybrid?

Measured by cost to drive, the Mercedes-Benz E-Class Plug-in Hybrid. The Alfa Romeo Giulia is rated 27 MPG combined and the Mercedes-Benz E-Class Plug-in Hybrid 59 MPGe + 23 MPG (EPA, most efficient configuration of each).

How much does it cost to fuel the 2025 Alfa Romeo Giulia vs. the Mercedes-Benz E-Class Plug-in Hybrid per year?

At 15,000 miles a year with $3.95/gal premium gas and 18¢/kWh electricity, about $2,194 for the Alfa Romeo Giulia and $1,847 for the Mercedes-Benz E-Class Plug-in Hybrid.

Which has more cargo space?

The Mercedes-Benz E-Class Plug-in Hybrid, with 13 cu ft of luggage volume versus 12 cu ft (EPA interior volume index).

Alfa Romeo Giulia vs Mercedes-Benz E-Class Plug-in Hybrid in other years

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