2025 head-to-head · Midsize Car

2025 Lexus ES vs Mercedes-Benz E-Class Plug-in Hybrid

MPG, range and what each one really costs you to fuel, from official EPA ratings and recalculated with your own gas and electricity prices.

Swap sides
✓ Cheaper to run
$1,661/ year to fuel
28 MPG
✓ Cheaper to run
$1,847/ year to fuel
59 MPGe + 23 MPG

AWD · 3.0L 6-cyl turbo · 9-speed automatic · 59 MPGe + 23 MPG

The 2025 Lexus ES is the cheaper one to run. Driving 15,000 miles a year with $3.10/gal regular gas, 18¢/kWh electricity and $3.95/gal premium gas, it costs about $1,661 a year to fuel (28 MPG), versus $1,847 for the 2025 Mercedes-Benz E-Class Plug-in Hybrid (59 MPGe + 23 MPG). That's roughly $186 a year, or about $932 over five years.

Your numbers

Change these to match your driving and local prices. Every figure and chart on this page updates.

Fuel cost over 10 years

  • Lexus ES
  • Mercedes-Benz E-Class Plug-in Hybrid

Side by side

Lexus ESMercedes-Benz E-Class Plug-in Hybrid
$1,661 Your annual fuel cost $1,847
28 MPG Combined efficiency 59 MPGe + 23 MPG
24 MPG City 54 MPGe / 21 MPG
33 MPG Highway 65 MPGe / 26 MPG
— Electricity use (kWh/100 mi) 57 kWh
— Driving range 410 mi
— All-electric range 43 mi
97 cu ft Passenger volume 100 cu ft
14 cu ft Cargo volume 13 cu ft
320 g/mi Tailpipe CO₂ (g/mi) 117 g/mi
6/10 EPA fuel economy score 7/10
6/10 EPA greenhouse gas score 9/10
— Charge time at 240V 2.8 hrs
Gas Powertrain Plug-in hybrid
Regular gasoline Fuel Premium gas + electricity
2.5L 4-cyl Engine / motor 3.0L 6-cyl turbo
8-speed automatic Transmission 9-speed automatic
AWD Drivetrain AWD

✓ marks the better value. EPA scores run 1–10 (10 is best). Volumes come from the EPA interior volume index and aren't published for every body style.

Lexus ES vs Mercedes-Benz E-Class Plug-in Hybrid across model years

  • Lexus ES
  • Mercedes-Benz E-Class Plug-in Hybrid

Annual fuel cost of the most efficient configuration of each model year, at your prices. Click a point to open that year.

How they differ

Per EPA interior volume figures, the Mercedes-Benz E-Class Plug-in Hybrid has more passenger space (100 vs. 97 cu ft); the Lexus ES has more cargo space (14 vs. 13 cu ft).

Among 42 2025 midsize cars, the Lexus ES ranks 21st and the Mercedes-Benz E-Class Plug-in Hybrid 23rd for lowest fuel cost.

The powertrains differ: the Lexus ES is a conventional gas model, while the Mercedes-Benz E-Class Plug-in Hybrid is a plug-in hybrid.

Frequently asked questions

Which is more fuel-efficient, the 2025 Lexus ES or the 2025 Mercedes-Benz E-Class Plug-in Hybrid?

Measured by cost to drive, the Lexus ES. The Lexus ES is rated 28 MPG combined and the Mercedes-Benz E-Class Plug-in Hybrid 59 MPGe + 23 MPG (EPA, most efficient configuration of each).

How much does it cost to fuel the 2025 Lexus ES vs. the Mercedes-Benz E-Class Plug-in Hybrid per year?

At 15,000 miles a year with $3.10/gal regular gas, 18¢/kWh electricity and $3.95/gal premium gas, about $1,661 for the Lexus ES and $1,847 for the Mercedes-Benz E-Class Plug-in Hybrid.

Which has more cargo space?

The Lexus ES, with 14 cu ft of luggage volume versus 13 cu ft (EPA interior volume index).

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