2025 head-to-head · Midsize Car
2025 Audi A6 Hybrid vs Mercedes-Benz E-Class Plug-in Hybrid
MPG, range and what each one really costs you to fuel, from official EPA ratings and recalculated with your own gas and electricity prices.
AWD · 3.0L 6-cyl turbo · 9-speed automatic · 59 MPGe + 23 MPG
The 2025 Mercedes-Benz E-Class Plug-in Hybrid is the cheaper one to run. Driving 15,000 miles a year with $3.95/gal premium gas and 18¢/kWh electricity, it costs about $1,847 a year to fuel (59 MPGe + 23 MPG), versus $2,279 for the 2025 Audi A6 Hybrid (26 MPG). That's roughly $432 a year, or about $2,159 over five years.
Your numbers
Change these to match your driving and local prices. Every figure and chart on this page updates.
Fuel cost over 10 years
- Audi A6 Hybrid
- Mercedes-Benz E-Class Plug-in Hybrid
Side by side
| Audi A6 Hybrid | Mercedes-Benz E-Class Plug-in Hybrid | |
|---|---|---|
| $2,279 | Your annual fuel cost | $1,847 |
| 26 MPG | Combined efficiency | 59 MPGe + 23 MPG |
| 24 MPG | City | 54 MPGe / 21 MPG |
| 31 MPG | Highway | 65 MPGe / 26 MPG |
| — | Electricity use (kWh/100 mi) | 57 kWh |
| — | Driving range | 410 mi |
| — | All-electric range | 43 mi |
| 99 cu ft | Passenger volume | 100 cu ft |
| 14 cu ft | Cargo volume | 13 cu ft |
| 339 g/mi | Tailpipe CO₂ (g/mi) | 117 g/mi |
| 5/10 | EPA fuel economy score | 7/10 |
| 5/10 | EPA greenhouse gas score | 9/10 |
| — | Charge time at 240V | 2.8 hrs |
| Hybrid | Powertrain | Plug-in hybrid |
| Premium gasoline | Fuel | Premium gas + electricity |
| 2.0L 4-cyl turbo | Engine / motor | 3.0L 6-cyl turbo |
| 7-speed dual-clutch | Transmission | 9-speed automatic |
| AWD | Drivetrain | AWD |
✓ marks the better value. EPA scores run 1–10 (10 is best). Volumes come from the EPA interior volume index and aren't published for every body style.
Audi A6 Hybrid vs Mercedes-Benz E-Class Plug-in Hybrid across model years
- Audi A6 Hybrid
- Mercedes-Benz E-Class Plug-in Hybrid
Annual fuel cost of the most efficient configuration of each model year, at your prices. Click a point to open that year.
How they differ
Per EPA interior volume figures, the Audi A6 Hybrid has more cargo space (14 vs. 13 cu ft).
Among 42 2025 midsize cars, the Audi A6 Hybrid ranks 29th and the Mercedes-Benz E-Class Plug-in Hybrid 23rd for lowest fuel cost.
The powertrains differ: the Audi A6 Hybrid is a full hybrid, while the Mercedes-Benz E-Class Plug-in Hybrid is a plug-in hybrid.
Frequently asked questions
Which is more fuel-efficient, the 2025 Audi A6 Hybrid or the 2025 Mercedes-Benz E-Class Plug-in Hybrid?
Measured by cost to drive, the Mercedes-Benz E-Class Plug-in Hybrid. The Audi A6 Hybrid is rated 26 MPG combined and the Mercedes-Benz E-Class Plug-in Hybrid 59 MPGe + 23 MPG (EPA, most efficient configuration of each).
How much does it cost to fuel the 2025 Audi A6 Hybrid vs. the Mercedes-Benz E-Class Plug-in Hybrid per year?
At 15,000 miles a year with $3.95/gal premium gas and 18¢/kWh electricity, about $2,279 for the Audi A6 Hybrid and $1,847 for the Mercedes-Benz E-Class Plug-in Hybrid.
Which has more cargo space?
The Audi A6 Hybrid, with 14 cu ft of luggage volume versus 13 cu ft (EPA interior volume index).
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